Compile Data Set for Download or QSAR
maximum 50k data
Found 635 of ic50 data for polymerid = 10533,49000944,50002975
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417722(CHEMBL1644207)
Affinity DataIC50:  0.0200nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417777(CHEMBL1644214)
Affinity DataIC50:  0.0501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205275(CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...)
Affinity DataIC50:  0.0900nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417721(CHEMBL1644206)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277668((R)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataIC50:  0.140nMAssay Description:Antagonist activity at DP1 in washed human platelet assessed as inhibition of PGD2-induced [125I]cAMP production preincubated 10 mins before PGD2 cha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277632((S)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataIC50:  0.220nMAssay Description:Antagonist activity at DP1 in washed human platelet assessed as inhibition of PGD2-induced [125I]cAMP production preincubated 10 mins before PGD2 cha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205274(CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...)
Affinity DataIC50:  0.260nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50060454((Z)-7-{(1R,2R,3S,5S)-2-[(5-Fluoro-benzo[b]thiophen...)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205276(CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...)
Affinity DataIC50:  0.290nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417759(CHEMBL1644213)
Affinity DataIC50:  0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417747(CHEMBL1644245)
Affinity DataIC50:  0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417771(CHEMBL1644247)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417764(CHEMBL1644227)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417725(CHEMBL1644211)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50060462((Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophe...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50128750(7-{2-[(5-Fluoro-benzo[b]thiophene-3-carbonyl)-amin...)
Affinity DataIC50:  0.420nMAssay Description:Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417726(CHEMBL1644212)
Affinity DataIC50:  0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417773(CHEMBL1644253)
Affinity DataIC50:  0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417723(CHEMBL1644208)
Affinity DataIC50:  0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357635(CHEMBL1915863)
Affinity DataIC50:  0.700nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350354(CHEMBL1813277)
Affinity DataIC50:  0.700nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417728(CHEMBL1644217)
Affinity DataIC50:  0.794nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50152512(CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...)
Affinity DataIC50:  0.810nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417763(CHEMBL1644224)
Affinity DataIC50:  0.891nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50128768(7-{2-[(5-Hydroxy-benzo[b]thiophene-3-carbonyl)-ami...)
Affinity DataIC50:  0.900nMAssay Description:Concentration required to inhibit the PGD-2 evoked cAMP formation in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357620(CHEMBL1915865)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50060462((Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophe...)
Affinity DataIC50:  1nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350350(CHEMBL1813120)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50152515(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataIC50:  1.20nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351492(CHEMBL1819617)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50060453((Z)-7-{(1R,2R,3S,5S)-2-[(6-Hydroxy-benzo[b]thiophe...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357636(CHEMBL1915866)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205275(CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...)
Affinity DataIC50:  1.40nMAssay Description:Activity at sheep DP receptor by PRP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357629(CHEMBL1915858)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350353(CHEMBL1813276)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350369(CHEMBL1813118)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351490(CHEMBL1819615)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50060454((Z)-7-{(1R,2R,3S,5S)-2-[(5-Fluoro-benzo[b]thiophen...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351490(CHEMBL1819615)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350361(CHEMBL1813289)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50128768(7-{2-[(5-Hydroxy-benzo[b]thiophene-3-carbonyl)-ami...)
Affinity DataIC50:  1.90nMAssay Description:Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50460667(CHEMBL4226404)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at DP1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50184212((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...)
Affinity DataIC50:  2nMAssay Description:Activity at DP receptor assessed as inhibition of PGD2-induced cAMP accumulation in plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50184212((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...)
Affinity DataIC50:  2nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50184217(2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...)
Affinity DataIC50:  2nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50184217(2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...)
Affinity DataIC50:  2nMAssay Description:Activity at DP receptor assessed as inhibition of PGD2-induced cAMP accumulation in plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350366(CHEMBL1813287)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350351(CHEMBL1813121)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50128767(7-{2-[(6-Hydroxy-benzo[b]thiophene-3-carbonyl)-ami...)
Affinity DataIC50:  2.20nMAssay Description:Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277668((R)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at DP1 in human platelet-rich plasma assessed as inhibition of PGD2-induced [125I]cAMP production preincubated 10 mins before PGD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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